High cholesterol: Could statins protect against motor neurone disease?

Researchers from Queen Mary University of London (QMUL) collaborated with the National Institute of Health (NIH) to conduct a big examine of knowledge. They’re the workforce who found the affiliation between excessive ldl cholesterol and motor neurone illness. Dr Alastair Nouce, from QMUL, mentioned: “This is the largest study to date looking at causal risk factors for motor neurone disease. “We noticed that increased ranges of LDL ldl cholesterol have been causally linked with a better danger of the illness.”

“Motor neurones management vital muscle exercise comparable to gripping, strolling, talking, swallowing and respiratory,” explained the charity.

“As these nerves are attacked, messages progressively cease reaching muscle groups. This initially results in weak spot and losing after which, ultimately, extreme paralysis and respiratory difficulties.”

A person’s mental capabilities aren’t usually affected, therefore a person is aware of their deteriorating condition.

One of the most famous cases of motor neurone disease is that of Professor Stephen Hawking.

Am I at risk of motor neurone disease?

Most people diagnosed with the condition are over the age of 50, although Professor Hawking received a diagnosis at 21 years old.

Data suggests that men are more at risk of developing the disease than women.

A small number of sufferers, up to 10 percent, have a family history of motor neurone disease.

However, this statistic also highlights that most cases of motor neurone disease aren’t thought to be linked to genetic susceptibility.

The devastating disease can kill a third of people diagnosed with the condition within one year.

Brain Research said: “There isn’t any treatment, and no efficient therapy.”

This is why QMUL researchers hope to evaluate “the usage of cholesterol-modifying medicine in folks susceptible to motor neurone illness”.

The body of work is published in journal Annals of Neurology.

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